NFL Week 3 Predictions: In-Depth Betting Analysis and Picks for Every Game on September 22, 2024

NFL Week 3 Predictions: In-Depth Betting Analysis and Picks for Every Game on September 22, 2024

Cleveland Browns vs. New York Giants (1:00 PM ET)

Spread: Browns -6.5

Moneyline: Browns -300, Giants +240

Total: 38.5

The Browns have opened their season strong, particularly at home. They boast one of the most formidable defenses in the league, anchored by Myles Garrett, while the Giants have been inconsistent on offense. Cleveland’s ability to shut down the run and apply pressure will put Giants' quarterback in uncomfortable positions, likely leading to turnovers. Given Cleveland's superior roster and home-field advantage, they are expected to win comfortably and cover the spread.

Pick: Cleveland Browns to cover (-6.5) and win on the moneyline.

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Green Bay Packers vs. Tennessee Titans (1:00 PM ET)

Spread: Titans -2.5

Moneyline: Titans -145, Packers +120

Total: 38

This game features two teams still finding their identities. The Titans, relying heavily on Derrick Henry’s ground game, will look to control the pace of the game. However, Green Bay’s young offense has shown flashes of explosiveness, and they’ve demonstrated resilience on the road. While the Titans' defense is stout, the Packers’ ability to stretch the field through their passing game could lead to an upset.

Pick: Green Bay Packers to cover (+2.5) and win outright on the moneyline.

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Houston Texans vs. Minnesota Vikings (1:00 PM ET)

Spread: Texans -2.5

Moneyline: Texans -125, Vikings +105

Total: 43.5

The Texans are narrow road favorites against a Vikings team that’s struggled with consistency. Houston’s defense, particularly their secondary, has performed admirably, while their offense, led by dynamic quarterback play, should find success against a shaky Vikings defense. Minnesota has been tough to trust, especially at home, where they have failed to cover the spread in recent games

[oai_citation:1,NFL - Houston Texans vs Minnesota Vikings Odds - Sunday September 22 2024](https://www.oddsshark.com/nfl/houston-minnesota-odds-september-22-2024-2160729).

Pick: Houston Texans to cover (-2.5) and win on the moneyline.

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Philadelphia Eagles vs. New Orleans Saints (1:00 PM ET)

Spread: Eagles -1

Moneyline: Eagles -115, Saints -105

Total: 44.5

This game pits two NFC powerhouses against each other. The Eagles, fresh off a deep playoff run, are slight road favorites against a Saints team that’s been impressive early in the season. New Orleans has historically been tough to beat at home, and their defense has held up well, especially in the red zone. However, Philadelphia’s high-octane offense, led by Jalen Hurts, may prove too much for New Orleans' defense to handle.

Pick: Philadelphia Eagles to cover (-1) and win on the moneyline.

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Los Angeles Chargers vs. Pittsburgh Steelers (1:00 PM ET)

Spread: Steelers -2

Moneyline: Steelers -130, Chargers +110

Total: 40

The Steelers have emerged as slight favorites in this matchup, thanks to their home-field advantage and defense, which continues to generate turnovers. On the other hand, the Chargers’ offense is dynamic, but they’ve struggled against more physical defenses. Pittsburgh’s ability to control the clock and force Justin Herbert into mistakes could be the deciding factor in this close game.

Pick: Pittsburgh Steelers to cover (-2) and win on the moneyline.

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Detroit Lions vs. Arizona Cardinals (4:05 PM ET)

Spread: Lions -3

Moneyline: Lions -160, Cardinals +140

Total: 46.5

Detroit is favored in this road matchup as they come in with one of the most potent offenses in the league. Arizona, on the other hand, has had a shaky start to the season and has struggled on defense, particularly against the pass. The Lions' aerial attack should thrive, making them the favorites to not only win but also cover the spread.

Pick: Detroit Lions to cover (-3) and win on the moneyline.

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Miami Dolphins (1-1) at Seattle Seahawks (2-0)

• Spread: Seahawks -4.5

• Moneyline: Seahawks (-210), Dolphins (+170)

Seattle’s strong start combined with Miami’s injury concerns make the Seahawks a solid pick at home. The Dolphins’ offense may struggle without key players, so expect Seattle to cover the spread and win .

Pick: Seahawks to cover (-4.5) and win on the moneyline.

San Francisco 49ers vs. Los Angeles Rams (4:25 PM ET)

Spread: 49ers -7.5

Moneyline: 49ers -350, Rams +275

Total: 45

The 49ers are significant road favorites as they face a depleted Rams team. With key offensive weapons out for Los Angeles, the Rams will have a tough time keeping pace with San Francisco’s balanced attack. The 49ers' defense, one of the best in the league, should dominate this matchup, forcing turnovers and keeping the Rams’ scoring opportunities limited.

Pick: San Francisco 49ers to cover (-7.5) and win on the moneyline.

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Baltimore Ravens vs. Dallas Cowboys (4:25 PM ET)

Spread: Ravens -1

Moneyline: Ravens -115, Cowboys -105

Total: 44.5

This could be one of the tightest contests of the day, as both teams enter with high expectations. The Ravens, despite being slight road favorites, need a bounce-back performance after a slow start to the season. Meanwhile, the Cowboys are trying to find consistency. Baltimore’s ability to control the clock with their run game and put pressure on Dak Prescott could tip the scales in their favor.

Pick: Baltimore Ravens to cover (-1) and win on the moneyline.

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Kansas City Chiefs vs. Atlanta Falcons (8:20 PM ET)

Spread: Chiefs -4.5

Moneyline: Chiefs -200, Falcons +170

Total: 47

The Chiefs, led by Patrick Mahomes, are road favorites against an Atlanta team still trying to find its rhythm. Kansas City’s offense is firing on all cylinders, and while the Falcons have made strides on defense, they lack the firepower to keep up with Mahomes and company. Expect the Chiefs to take control early and cover the spread with relative ease.

Pick: Kansas City Chiefs to cover (-4.5) and win on the moneyline.

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Conclusion:

This Week 3 slate offers a wide range of close matchups and potential blowouts. Teams like the Browns, Eagles, and 49ers should have little trouble covering their spreads, while the Packers and Texans are poised for potential upsets. As always, betting smart and keeping an eye on injuries and late developments will be key.

Here are the sources referenced for the NFL game analysis article for September 22, 2024:

1. Sporting News - Week 3 NFL odds, betting lines, and spreads for each game [oai_citation:5,NFL Week 3 betting odds, lines, point spreads and over/under totals for every 2024 football game | Sporting News](https://www.sportingnews.com/us/nfl/news/nfl-week-3-betting-odds-lines-point-spreads-over-under-totals/3ccbafbdbf51ccec2836ab74).

2. Odds Shark - Detailed betting trends and team stats for matchups like Texans vs. Vikings [oai_citation:4,NFL - Houston Texans vs Minnesota Vikings Odds - Sunday September 22 2024](https://www.oddsshark.com/nfl/houston-minnesota-odds-september-22-2024-2160729).

3. Vegas Insider - Comprehensive NFL odds and insights for Week 3 matchups [oai_citation:3,NFL Odds & Lines 2024-25 | NFL Week 3 Odds](https://www.vegasinsider.com/nfl/odds/las-vegas/).

4. Dimers - Advanced predictive analytics and moneyline recommendations for key games [oai_citation:2,NFL Best Bets: Week 3 Picks Include Two Moneyline Plays [9/22/2024]](https://www.dimers.com/news/nfl-best-bets-today-ac-sunday-september-22-2024).

5. Sports Betting Dime - Latest betting lines, spreads, and betting insights for the NFL in Week 3 [oai_citation:1,NFL Odds: Latest Football Betting Lines & Spreads](https://www.sportsbettingdime.com/nfl/odds/).

These sources provide updated betting lines and trends, helping to shape the predictions for each game.

Disclaimer:

The information provided in this article is intended for informational and entertainment purposes only. While every effort has been made to ensure the accuracy of betting lines, predictions, and analysis at the time of publication, odds may change leading up to game day. Readers should exercise caution and perform their own research before making any wagers. The author and publisher do not take responsibility for any losses incurred based on the information provided in this article. Betting involves financial risk, and it is important to gamble responsibly. If you or someone you know has a gambling problem, please seek help from appropriate resources.

Always check the latest odds and consult official sources for up-to-date information.

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Last updated September 06, 2023

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